To study the effect of Cocos nucifera oil when incorporated into tissue conditioner on its tensile strength and antifungal activity: An in vitro study

To study the effect of Cocos nucifera oil when incorporated into tissue conditioner on its tensile strength and antifungal activity: An in vitro study

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Aim: This study aims to test the tensile strength and growth of Candida albicans turbo air m3f24-1-n on Viscogel tissue conditioner when incorporated with coconut oil (CCO) and to compare its efficacy with other antifungal agents.Settings and Design: Evaluative - In-vitro study design.Materials and Methods: Fifty dumbbell-shaped samples (n = 10) of Viscogel tissue conditioner were fabricated according to ASTM standard and were classified into 5 groups (10% CCO, 30% w/w tea tree oil, 5% w/w fluconazole, 0.

03% w/w silver nanoparticles, and plain tissue conditioner).These samples were compared and evaluated for their tensile strength.Further to test the antifungal activity, a total of 60 samples (n = 15) were fabricated, each group (n = 15) was further divided into hobbit door for sale three subgroups (n = 5), namely 24-h, 3-day, and 5-day period, which were inoculated in sabouraud dextrose agar plate to test for the growth of C.

albicans.Statistical Analysis Used: Oneway ANOVA and post hoc Tukey honestly significant difference test.Results: 10% w/w CCO yielded a mean tensile strength of 20.

06 as compared to the plain tissue conditioner which showed a mean tensile strength of 17.81.Similarly, 10% w/w CCO incorporated into Viscogel tissue conditioner showed a significant reduction in the colonization of C.

albicans on the 5th day.Conclusions: 10% w/w of CCO when mixed with Viscogel tissue conditioner showed a significant reduction in the growth of C.albicans, and addition of the same increased the tensile strength of the tissue conditioner.